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Sandoz Launches PYZCHIVA® (Ustekinumab) Autoinjector in Europe

On May 21, 2025, Sandoz announced the commercial launch in Europe of its PYZCHIVA® (ustekinumab) autoinjector, “the first ustekinumab biosimilar in Europe commercially available in an autoinjector.”...more

Amneal Launches FYLNETRA (pegfilgrastim-pbbk) in the United States

Last week, Amneal announced the launch of FYLNETRA (pegfilgrastim-pbbk), a biosimilar to Amgen’s NEULASTA, in the United States.  According to the press release, FYLNETRA—Amneal’s third biosimilar launch in the United States...more

Mabwell Announces Approval of Denosumab Biosimilar MAILISHU in China

​​​​​​​On March 31, 2023, Mabwell announced that China’s National Medical Products Administration (NMPA) has approved MAILISHU, a denosumab biosimilar, for the treatment of osteoporosis in postmenopausal women at high risk of...more

Biosimilar Clinical Trial Updates - February 2023

Big Molecule Watch monitors for biosimilar clinical trial results. Here we report on four recent announcements concerning biosimilars of natalizumab, trastuzumab, daratumumab, and aflibercept....more

Amgen Launches AMJEVITA - First Biosimilar to HUMIRA in the United States

Amgen announced today the launch of AMJEVITA (adalimumab-atto), a biosimilar to AbbVie’s HUMIRA (adalimumab), in the United States.  AMJEVITA was the first HUMIRA biosimilar approved by the FDA and is now the first to be...more

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