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BYOOVIZ® (Ranibizumab-Nuna) Granted Interchangeable Status

Recently, Biogen and Samsung Bioepis’s ranibizumab biosimilar (BYOOVIZ) was granted interchangeable status by the U.S. Food and Drug Administration. BYOOVIZ was deemed interchangeable to Genentech’s LUCENTIS for the treatment...more

Infliximab Clinical Trial Updates

The Big Molecule Watch is monitoring clinical trial activities involving infliximab. Here we report on recent studies with Celltrion’s INFLECTRA (infliximab-dyyb). ...more

FDA Testimony Before the U.S. Senate Regarding User Fee Agreements

This week Patrizia Cavazzoni (Director, CDER), Peter Marks (Director, CBER), and Jeffrey Shuren (Director, CDRH) of the FDA testified before the committee on Health Education, Labor and Pensions of the U.S. Senate regarding...more

Coherus and Junshi Biosciences Announce FDA Acceptance of Toripalimab BLA

Last week, Coherus and Junshi Biosciences announced that the FDA accepted their BLA for toripalimab in combination with gemcitabine and cisplatin for the first-line treatment of patients with advanced recurrent or metastatic...more

FDA Schedules Public Meeting and Request for Comments on Biosimilar User Fee Act

Last week, FDA issued a notice of public meeting and request for comment relating to proposed recommendations for the reauthorization of the Biosimilar User Fee Act (“BsUFA”) for fiscal years 2023 to 2027. We have previously...more

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