Depo-Provera has been used by millions of women as a convenient and long-lasting contraceptive option. However, recent concerns have emerged about a possible link between the long-term use of these injections and the development of meningiomas, a type of brain tumor.
Several lawsuits have been filed against Pfizer, the manufacturer of Depo-Provera, claiming that it failed to warn women about this potential risk. But what does the science say about a connection between birth control injections and meningiomas?
This article explains what a meningioma is, how hormones like progestin may influence its growth, and what you should do if you have developed a meningioma after using Depo-Provera.
What Is a Meningioma?
A meningioma is a tumor that forms in the meninges, the protective layers surrounding the brain and spinal cord. These tumors are usually benign (non-cancerous) but can still cause significant health issues depending on their size and location.
Common Symptoms of Meningiomas
- Headaches
- Blurred or double vision
- Memory loss or confusion
- Seizures
- Weakness or numbness in arms or legs
While meningiomas typically grow slowly, they can press against the brain, nerves, or blood vessels, leading to serious neurological problems. Treatment often involves surgery, radiation therapy, or medication to manage symptoms.
How Is Depo-Provera Linked to Meningiomas?
Depo-Provera is a birth control injection that contains medroxyprogesterone acetate (MPA), a synthetic form of progestin. This hormone helps prevent pregnancy by stopping ovulation and thickening cervical mucus.
However, research suggests that long-term exposure to high levels of progestin may encourage meningioma growth. Many meningiomas have progesterone receptors, meaning they respond to hormones like progestin, which may fuel their development.
Scientific Studies on the Connection
A 2024 study published in The BMJ examined the use of progestogen-based medications and the risk of developing intracranial meningiomas. The researchers found that medroxyprogesterone acetate, the active ingredient in Depo-Provera, was associated with an increased risk of meningioma. The study also concluded that the risk grew higher with prolonged use of the drug.
This research builds on previous findings from European health authorities, including a 2019 advisory from French regulators that warned of a higher risk of meningiomas among women using high-dose progestin-based contraceptives.
These studies provide strong evidence that prolonged exposure to high-dose progestin, like that found in Depo-Provera, is linked to an increased risk of meningioma, raising serious concerns about the safety of this contraceptive for long-term users.
The Basis of the Lawsuits
As more research develops that links Depo-Provera to meningiomas, women who developed these tumors after long-term use have filed lawsuits against the manufacturer, Pfizer.
The key claims in these lawsuits include:
- Failure to warn – Pfizer did not adequately inform consumers or doctors about the potential risk of meningiomas associated with Depo-Provera.
- Defective drug design – The lawsuit argues that the formulation of Depo-Provera may pose an unreasonable health risk.
- Negligence – Plaintiffs claim that Pfizer ignored or downplayed evidence suggesting a link between progestin and meningioma development.
Some lawsuits have led to updated warnings on Depo-Provera labels in certain countries, but litigation is ongoing in the United States as more women come forward with claims.
What Should I Do If I Was Diagnosed With a Meningioma?
If you have used Depo-Provera and been diagnosed with a meningioma, you may be wondering what steps to take next. Here’s what you should do:
1. Seek Medical Care
Your health should be the top priority. Work with a neurologist or specialist to understand your diagnosis and discuss potential treatment options. Keep detailed records of your medical visits, tests, and any prescribed treatments.
2. Review Your Birth Control History
Gather any records you have of your Depo-Provera use, including prescription details, pharmacy records, and doctor’s notes. This documentation can help establish a connection between your use of the drug and your diagnosis.
3. Consult a Personal Injury Attorney
Speaking with an attorney can help you understand whether you may have a legal claim. A lawyer can:
- Review your medical history and birth control use
- Determine if you qualify for a lawsuit
- Help gather the necessary evidence to support your case
4. Take Action
Many affected women are filing lawsuits against Pfizer for the harm they have suffered for harm caused by Depo-Provera use. If you qualify, taking legal action may help you seek compensation for medical bills, lost wages, pain and suffering, and other damages.
Can You Get Compensation?
If you have developed a meningioma after using Depo-Provera, you may be eligible for financial compensation. Potential damages could include:
- Medical expenses – Covering costs for diagnosis, surgery, radiation, and follow-up care.
- Lost wages – Compensation for time off work due to medical treatments or disability.
- Pain and suffering – Acknowledging the physical and emotional distress caused by the tumor.
- Loss of quality of life – If your condition has permanently affected your ability to work or engage in daily activities.
Get Legal Help Today
The growing evidence linking Depo-Provera to meningiomas has led to legal action, as more women seek justice for the serious health risks they were not warned about. If you or a loved one has developed a meningioma after using a birth control injection, you may have legal options.
